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Physical Activity, Sedentary Time Linked to Heart Failure in Men
After adjustment for confounding variables, low physical activity, high sedentary time increase risk

FRIDAY, Jan. 24, 2014 (HealthDay News) -- For middle-aged men, physical activity and sedentary time are associated with the risk of heart failure, according to a study published in the January issue of Circulation: Heart Failure.

Deborah Rohm Young, Ph.D., from Kaiser Permanente Southern California in Pasadena, and colleagues examined the correlation between physical activity and prolonged sedentary time on heart failure. The authors used data for 82,695 men aged 45 years or older from the California Men's Health Study without prevalent heart failure. Participants were followed for 10 years.

During a mean follow-up of 7.8 years, the researchers identified 3,473 men diagnosed with heart failure. After adjustment for confounding variables, including sedentary time, sociodemographics, hypertension, diabetes mellitus, unfavorable lipid levels, body mass index, smoking, and diet, the hazard ratio for heart failure was 1.52 in the lowest versus the highest physical activity category. Increased risk was also seen for those in the medium physical activity category (hazard ratio, 1.17). After adjustment for the same variables and physical activity, the hazard ratio for heart failure was 1.34 in the highest versus the lowest sedentary category and 1.13 for the medium sedentary time category. Similar trends were seen for white and Hispanic subgroups and across body mass index categories, baseline hypertension status, and prevalent coronary heart disease.

"In conclusion, the results from this large, prospective study of a racially/ethnically diverse population bolster the accumulating evidence of the importance of a physically active and nonsedentary lifestyle for reducing the risk of heart failure," the authors write.

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